The Rays opened their series against the Red Sox with a 5-3 win at Fenway Park.
Zach Eflin earned the victory after striking out two and allowing three runs over five innings pitched.
Jason Adam secured his third save of the season after striking out three batters in a scoreless bottom of the ninth.
Amed Rosario led the way at the plate after going two for four with a two-run triple and an RBI double.
Tampa Bay is now 21-and-21. Kutter Crawford was tagged with the loss after allowing four runs on seven hits over six innings of work.
Tyler O'Neill went deep for the 10th time this season after hitting a three-run shot in the bottom of the first. Boston is now 21-and-20.
(Photo by Brian Fluharty/Getty Images)